Abstract

Roxb, (Sterculiaceae). The diuretic assay was done on both healthy wistar rats and rabbits. The dose used for the diuretic assay was 100, 200 & 400mg/kg of the extract. Compared to the control and standard drug furosemide (20mg/kg), the result of diuretic study showed dose dependent activity of the extracts. The result also indicated higher excretion of Na , K

Highlights

  • Sterculia villosa Roxb, (Sterculiaceae) are deciduous tree with grey or brown bark covered with corky nodules commonly known as 'Udal' or 'Udar'

  • Evaluation of anthelmintic activity was compared with reference standard drug Albendazole

  • The ethanolic extract of Sterculia villosa barks were found to be effective upon comparison with the Standard drug albendazole in causing paralysis and death of earthworms

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Summary

Introduction

Sterculia villosa Roxb, (Sterculiaceae) are deciduous tree with grey or brown bark covered with corky nodules commonly known as 'Udal' or 'Udar' It is one of the fast-growing plant species, has large long-stalked deeply lobed leaves and yellow flowers (Joshi, 2011). The diuretics are useful in the treatment of ascites, congestive cardiac failure, and edema of the lungs, kidneys and liver. In these conditions fluid abnormally accumulates in the body. Diuretics increase the excretion of Na+ which may induce antihypertensive effect Such compounds may act on nephron in the kidney leading to a decrease in the re-absorption of water and subsequently increased urine output (Singh and Dixit, 1992)

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