Abstract

Timely diagnostics and treatment of cytomegalovirus infection in pregnant women and newborns allow to avoid serious consequences, preserving the life and health of the child. The article provides an example of antenatal diagnosis of congenital cytomegalovirus infection in the fetus (positive result of polymerase chain reaction in umbilical cord blood), treatment with umbilical transfusion of donor red blood cells, postnatal therapy with antiviral drugs, including ganciclovir and specific immunoglobulin. The issues of assessing the risk of congenital cytomegalovirus infection, approaches to its prevention and treatment during pregnancy are discussed.

Highlights

  • Diagnostics and treatment of cytomegalovirus infection in pregnant women and newborns allow to avoid serious consequences, preserving the life and health of the child

  • The article provides an example of antenatal diagnosis of congenital cytomegalovirus infection in the fetus, treatment with umbilical transfusion of donor red blood cells, postnatal therapy with antiviral drugs, including ganciclovir and specific immunoglobulin

  • Цитомегаловирусная инфекция – наиболее распространенная в экономически развитом мире врожденная инфекция; ее частота варьирует от 0,3 до 3,0% (в России – от 0,1 до 2,8%) [1,2,3,4]

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Summary

Introduction

Diagnostics and treatment of cytomegalovirus infection in pregnant women and newborns allow to avoid serious consequences, preserving the life and health of the child. Анте- и постнатальная диагностика и комплексное лечение врожденной цитомегаловирусной инфекции. Распространенность цитомегаловирусной инфекции среди женщин репродуктивного возраста в большинстве стран мира колеблется от 50 до 80%; от 1 до 4% серонегативных женщин инфицируются цитомегаловирусом во время беременности впервые (первичная цитомегаловирусная инфекция) [1,2,3,4].

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