Abstract
ABSTRACT The development of a post operative infection following the implantation of a foreign material, such as a total joint prosthesis, is one of the most feared complications in orthopedic surgery. Prevention of such bacterial infections is best accomplished through the delivery of antibiotics as close to the implant as possible. A novel method has been developed to attach, retain and release antibiotics from titanium based materials. This technique consists of forming porous surface coatings by anodizing and using the surface chemical properties of the oxide coatings to attach antibiotics. Coatings with pores in the size range 0.1 to 10 urn have been formed in acid as well as basic solutions. The thickness, stoichiometry and morphology of the coatings have been characterized by Rutherford backscattering spectrometry and electron spectroscopy techniques. The isoelectric point of the coatings has been measured by a streaming potential technique. The attachment and retainment of gentamicin sulfate, a ca...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
