Abstract
Abstract. Relevance. The combination of acute myocardial infarction (AMI) and type 2 diabetes mellitus (DM2) entails early disability and mortality of the population, including among people of working age. The study of long-term outcomes of AMI in patients with type 2 diabetes is necessary to improve secondary prevention programs and reduce cardiovascular mortality. Aim of the study. To evaluate the prognosis of myocardial infarction in combination with type 2 diabetes mellitus for 1 year. Material and methods. He main group consisted of 115 patients with AMI and DM 2 (55 men and 60 women, the average age of patients was 63,2±5,3 years, men 62,3±5,5 years, women 64,3±4,9 years). The comparison group included 116 patients with AMI without concomitant DM 2 (in the comparison group 60 men, 56 women (mean age of patients 63,6±5,4 years, men 62,1±4,2 years, women 65,2±5,7 years). 12 months after the inclusion of patients in the study, an assessment of "endpoints" was carried out. Statistical data analysis was carried out using the modules of the SPSS Statistics 23.0 program. Results. It was revealed that a history of type 2 diabetes increases the risk of cardiovascular death by 7.9 times (OR 7,929, 95% CI 1,758-35,758, p=0,002), 2.1 times (OR 2,138, 95% CI 1,050- 4,353, p= 0,034) the risk of repeated hospitalizations for myocardial ischemia. The annual unfavorable prognosis of AMI is affected by: a history of coronary artery disease (OR 5,653 CI 2,114- 5,114, p≤ 0,001); CHF II-IV FC according to NYHA (OR 4,316 CI 0,916-20,330, p= 0,048); multivessel coronary lesion (OR 4,759 CI 1,018-22,248, p= 0,032); anterior localization of AMI (OR 3,646 CI 1,630-8,156, p=0,01); brachiocephalic artery stenosis (OR 4,278 CI 1,042- 17,559, p=0,031); stage 3-4 chronic kidney disease (OR 6,406 CI 2,589- 15,852, p≤0,01); obesity (OR 2,368 CI 1,086- 5,164, p= 0,029). Conclusion. The ideas about the annual outcomes of AMI in combination with type 2 diabetes in patients treated with modern methods of reperfusion therapy have been expanded.
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