Abstract
A FEW YEARS BACK, THE 50TH anniversary of the discovery of the structure of the DNA double helix by biologists James D. Watson and Francis H. C. Crick was grandly celebrated. Last month marked a less celebrated anniversary: 50 years since the discovery of the RNA double helix. It was in the July 20, 1956, Journal of the American Chemical Society ( 78 , 3548) that Alexander Rich and David R. Davies of the National Institute of Mental Health, in Bethesda, Md., reported for the first time that RNA could form a double helix. Rich is now professor of biophysics at Massachusetts Institute of Technology, and Davies is chief of the molecular structure section in the laboratory of molecular biology at the National Institute of Diabetes & Digestive & Kidney Diseases, in Bethesda. In fact, it's a double anniversary. It's also 50 years since the discovery of the nucleic acid hybridization reaction—the reaction of two unstructured polynucleotides to form a ...
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