Abstract

Escherichia coliis able to produce different infections in humans. It pathogenicity in the female genital tract is unknown. To determine the presence of virulence genes (VG) in E. colistrains isolated from the female genital tract. 146 E. colistrains isolated as monomicrobial cultures from vaginal infections were genetically characterized by search of hly, iucC, afa, fimH, neuC, sfa/foc, cnF1, papC, usp,and ibeAVG. Studies were performed by means PFGE and PCR. Genetic analysis of the strains showed two groups with a similarity of approximately 80%. The similarity genetic intragroup was approximately 95%. The results showed strains with a high number of VG and the most common were cnf1andfimH.The afagene was not detected. Were identified eight VG combinations and the most common was papC+ hly+ iucC+ afa- neuC- fimH+ sfa/foc+ cnf1+ usp+ ibeA-. The studied strains are concentrated in two genetic groups. Most of the strains contain a great number of VG present in E. coliisolated from extraintestinal infections. It is important to develop new research strategies in this area, to deepen the phylogenetic knowledge of these strains and confirm their true role in vaginal infection.

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