Abstract
Antibodies to oxidized lipoproteins are useful markers for diagnosis and prognosis of some heart diseases. Low density lipoproteins (LDL) were purified from human plasma and were oxidized by CuCl2. They were immobilized on anisotropic silver nanoparticles with tunable plasmon resonance band and were applied for detection of appropriate antibodies in sera of patients with stenosis. The presence of such antibodies brings to significant shifting of plasmon resonance band to long-wave region in comparison with control sera. This approach permits to detect such antibodies by rapid method with one step procedure.
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