Abstract
Under natural conditions the skin of man and animals is exposed to numerous agents and may be subject to infections by various pathogenic organisms, including viruses, bacteria, and fungi. In predisposed individuals or those exposed to large concentrations of pathogens, the infection is more pronounced, more invasive, more extended, and less susceptible to therapeutic agents. There are a number of uncommon organisms that are often considered to be saprophytic yet turn to be infectious agents. In this chapter the most common fungal pathogens used as test species in animal models for dermatomycoses are discussed, and the usefulness of the animal models for studying infection and screening antifungal compounds is evaluated.
Published Version
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