Angiotensin-converting enzyme inhibitor reduces proadhesive activity of neointimal smooth muscle cells through attenuating constitutive NF-kB activity

Abstract

RESULTS: During the study period, 63 patients met inclusion criteria. Mean pre-procedural observation was 36( / 24) months and mean follow-up was 11.7( / 9) months. Renal impairment occurred in 30% of patients, whereas 65% experienced a worsening inverse creatinine slope. With multivariate analysis, the presence of intrinsic nephropathy and worsening creatinine slope were independent predictors of renal impairment during the follow-up period (P 0.05). Table. Independent Predictors of Developing Renal Insufficiency After TRF for EVAR