Angioinvasive aspergillosis with halo sign on computed tomography of the lungs

Abstract

(Figure B). Chest radiography in angioinvasive aspergillosis cases is usually nonspecific, with multiple ill-defined nodular opacities. CT scans may show nodules with the characteristic halo sign. This sign is composed of a ground-glass halo that surrounds a denser central nodule. The central nodule corresponds to a septic infarct, while the halo corresponds to the presence of a hemorrhage. O paciente de 26 anos, com linfoma linfoblastico de celulas T, na fase de consolidacao da quimioterapia (13a semana), em uso de ARA-C/mitoxantrone, apresentou quadro de neutropenia febril. Ele foi submetido a tomografia computadorizada (TC) do torax de alta resolucao, que evidenciou um nodulo pulmonar com o