Abstract

• - Vasculogenesis, angiongenesis and arteriogenesis • • Angiogenesis in embryonic development vasculogenesis • • Angiogenesis • - Vessel formation • - Mechanical hypothesis • - Biological hypothesis: role of the angiogenic growth factors FGF and VEGF • • Combined hypothesis: angiogenesis and vascular remodelling • - Therapeutic angiogenesis in cardiovascular diseases • • Critical limb ischemia • • Myocardial ischemia • - Gene therapy • - Angiogenic growth factor therapy • - Tumour angiogenesis • - Angiogenesis in healing wounds

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