Abstract
Anaphylaxis is a severe, systemic hypersensitivity reaction characterized by rapid in onset with potentially life-threatening. The prevalence of anaphylaxis has been estimated at 1.6% to 5.1% and increasing nowadays. Drug-Induce-Anaphylaxis is one the most cause of fatal anaphylaxis. A 26-year-old male with anaphylaxis shock due to drug-induced with total IgE as a diagnostic support test. Anaphylaxis is a multisystem allergic emergency. Early recognition and prompt administration of epinephrine remain the cornerstone of management due to its rapid progression.
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