Abstract
Aims: To analyse impact of different implant placement timings on the esthetic stability of a single implant restoration in maxillary anterior region. Materials and methods: The systematic review and meta-analysis adhered to the PRISMA guidelines and were registered in the PROSPERO database. In addition to systematic searches on the national library of medicine (MEDLINE PubMed), Cochrane library, Google Scholar, and EbscoHost, manual searches were also conducted to identify articles published from January 1, 2000, to December 1, 2020. The included studies comprised randomized controlled trials, as well as prospective and retrospective cohort clinical studies. The assessment of risk of bias employed the Cochrane Collaboration's tool, MINORS tool, and a quality appraisal checklist. Utilizing the Review Manager software tool, a meta-analysis was conducted, and the robustness of the meta-analytic findings was duly evaluated. Results: Out of 313 studies screened, seven met the predetermined inclusion and exclusion criteria for incorporation into the systematic review. The meta-analysis disclosed an effect on marginal bone loss associated with different implant placement timings. However, the overall impact on esthetic stability was not statistically significant. Furthermore, there is moderate evidence suggesting a decrease in marginal bone loss following immediate implant placement, with a mean difference of -0.33mm. Conclusions: The timing of implant placement appears to have some impact on both marginal bone loss and pink esthetic score. However, no statistically significant difference was observed when comparing various implant placement timings in terms of pink esthetic score and marginal bone loss. The evidence lacked sufficient strength to firmly support the aforementioned observations, emphasizing the need for additional well-designed randomized clinical trials to draw definitive conclusions. Conflict of interest statement: The author reports no conflicts of interest related to this study.This study received no external funding.
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