Analytical Study of Zinc-Oxide Nanoparticles for Human Health

Abstract

Pure nanoparticles for medical applications more than 400 enzymes and hormones and play a curious part in the health of our skin, teeth, bones, hair, nails, muscles, nerves and brain function have attracted much attention due to their enhanced biocompatibility and multifunctional, antibacterial, antifungal, antiviral properties making them suitable for many applications such as prednisolone delivery systems and nanotherapy. Among Nanomaterials, zinc oxide nanoparticles (ZnO NPs) have been extensively studied due to their unique physical and chemical properties. High surface-to-volume ratio together with small size, antibacterial activity, photocatalytic and semiconductor properties make ZnO NPs a new generation of anticancer agents in physiotherapy, reactors Nano bioreactors and bone stimulants for bone tissue regeneration. However, ZnO NPs have limited stability and can be used in biological environments. ZnO NPs also exhibit unpredictable cytotoxic effects. To overcome the above limitations and further expand the use of ZnO NPs in nanomedicine, doping seems to be a promising solution. This theoretical review reveals important achievements in using ZnO-doped nanoparticles for applications in nanomedicine. Sol-gel, hydrothermal and combustion methods are commonly used to fabricate rare-earth and transition metal-doped ZnO NPs. The theoretical results indicate that the doping of ZnO NPs is a valuable tool to improve their biomedical properties compared with undoped NPs, opening up new possibilities for ZnO NPs in nanomedicine.