Analysis the effect of aripiprazole combined with psychological behavior intervention on tic disorders in children

Abstract

Objective To explore the improvement effect of aripiprazole combined with psychological behavior intervention on tic disorders in children. Methods The clinical data of 87 children with aripiprazole from January 2015 to January 2017 were divided into the study group (46 cases) and the control group (41 cases) according treatment methods. The control group was given aripiprazole tablets oral treatment. The children in the study group were given psychological intervention on the basis of the control group. The Yale comprehensive pumping severity scale (YGTSS) was used to evaluate the effect of two groups before and after treatment. Results The total effective rates of the study group and the control group were 91.3%(42/46) and 75.6%(31/41), respectively. The difference between two groups was statistically significant (P 0.05). The YGTSS scores of situation of movement and sound movement after treatment were significantly decrease than those before treatment [control group: (6.73 ± 2.44) scores vs. (15.36 ± 2.10) scores, (4.62 ± 1.88) scores vs. (9.58 ± 3.72) scores; study group: (2.81 ± 2.05) scores vs. (6.73 ± 2.44) scores, (2.17 ± 1.83) scores vs. (9.62 ± 3.67) scores] (P<0.01). After treatment, the YGTSS scores of situation of movement and sound movement in study group were significantly lower than those in control group (P<0.01). Conclusions Psychological and behavioral intervention can significantly improve the efficacy of aripiprazole in children with tic disorders. Key words: Tic disorder; Aripiprazole; Psychological intervention