Analysis of viral etiology of 254 acute respiratory infection cases

Abstract

Objective To analyze the viral etiology of acute respiratow infection,and to study the activity and epidemiological characteristic of main pathogens,so as to establish pathogen spectrum of acute respiratory infection in Fengtai district of Beijing.Methods Basic information and throat swabs of acute respiratory infection cases during 2010-2012 were collected.Influenza virus,respiratory syncytial virus,adenovirus,parainfluenza virus,metapneumovirus,coronavirus,rhinovirus,human Boca virus and mycoplasma pneumonia were detected by multiplex PCR and RT-PCR.SPSS 17.0 was used for data analysis.Results 154 were positive in all of the 254 samples,the positive ratio was 60.63％.Influenza viruses,parainfluenza virus and mycoplasma pneumoniae were the most frequently detected pathogens in winter and spring.Parainfluenza and mycoplasma were the only detected pathogens in summer.There was no significant difference in positive rate between male and female patients.Influenza viruses and parainfluenza virus were the major viral pathogens of influenza-like illness,mycoplasma pneumoniae was the major pathogen of pneumonia patients.Influenza A was dominate during 2010-2011,while influenza B as the major one during the 2011-2012 influenza season.Conclusions Influenza virus,mycoplasma pneumoniae,and parainfluenza virus were the main pathogens leading to acute respiratory infection during 2010-2012 in Fengtai district of Beijing.The major pathogens were different in different seasons. Key words: Acute respiratory tract infection; Pathogen spectrum; Viral etiology