Abstract
Thyroid hormones play an important role during pregnancy, providing organogenesis, growth and development of the fetus, teach in the formation and development of the brain and its structure, influencing cognitive abilities. Thyroid dysfunction is associated with the pathological course of pregnancy and childbirth, as well as a negative effect on the fetus. Iodine deficiency, which persists throughout Uzbekistan, creates prerequisites for more frequent development of subclinical hypothyroidism and hypothyroxinemia of pregnant women. Therefore, early detection of thyroid dysfunction during gestation in regions of iodine deficiency is relevant. Chronic iodine deficiency leads to a wide range of pathology, united by the term "iodine deficiency diseases" (IDD). In addition to diseases of the thyroid gland (thyroid gland), IDZ involve pathological conditions suspended by a relative deficiency of thyroid hormones: violation of reproductive function, miscarriage of pregnancy, emerging anomalies and stillbirths, replacement of growth and development of the child, as well as cognitive disorders. Therefore, iodine deficiency is most dangerous at the stage of intrauterine development of the child and in early childhood due to the great importance of thyroid hormones in the formation of the structure of the brain and the development of intelligence. Reminders of mild iodine deficiency in the regions leads to a decrease in mental abilities, mental health disorders and a weakening of the physical development of the child.
Highlights
KEYWORDS Iodine deficiency, pregnant women, thyroid gland, thyrotoxicosis, hypothyroidism, iodine deficiency diseases
To assess the thyroid status in pregnant women in regions of iodine deficiency
Out of 350 pregnant women who registered for a women's consultation within six months, 208 were excluded by the hairstyle of non–compliance with the inclusion and exclusion criteria: late treatment (n = 62), thyroid pathology in the anamnesis (n = 61: subclinical hypothyroidism – 48, AIT – 4, nodular goiter – 4, gestational thyrotoxicosis – 3, Graves' disease in the anamnesis – 2, hemistrumectomy on the occasion of nodular goiter - 2), cancellation from participation (N = 51), the impossibility of further observation (N = 34)
Summary
KEYWORDS Iodine deficiency, pregnant women, thyroid gland, thyrotoxicosis, hypothyroidism, iodine deficiency diseases. Purpose: To assess the thyroid status in pregnant women in regions of iodine deficiency.
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