Abstract

Objective: The compatibility law of Allium tuberosum Rottler was discussed based on association rule analysis. Methods: With "Allium tuberosum Rottler" as the subject, from January 1998 to October 2018, the search was conducted in the advanced search interface of the database of CNKI and Wanfang Medical Net, and 48 literatures meeting the standards were included. Using Excel 2013, SPSS Modeler 14.1 and SPSS Statistics 19.0 statistical software as tools, frequency analysis and association rule analysis were conducted for the Chinese medicine included in the standard. Results: Frequency analysis found that among the 48 groups included in the standard, Allium tuberosum Rottler (48 times, 100%), Astragalus membranaceus (Fisch.) Bunge (11 times, 22.9%), appeared most frequently. In the statistics of sexual flavor of single drug with frequency of 5 or more, sweet(15 times, 55.6%),Pungent(4 times, 14.8%)was the most common; Kidney meridian(14 times, 31.1%),Liver meridian(9 times, 20.0%was the most common; There were 7 kinds of common TCM diseases, most of which were prepubertal diseases. Nine drug pairs with the highest intensity of association were obtained in association rule analysis. Conclusion: By applying modern information technology and combining TCM clinical data with big data for in-depth analysis and integration, it will be more convenient to explore the potential compatibility law of TCM, and finally feedback to clinical practice, providing basis for guiding the research and development of clinical medication and new prescription.

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