Analysis of the related risk factors of bleeding esophageal varices of cirrhosis

Abstract

Objective To explore the related risk factors of esophageal variceal bleeding(BEV). Methods 69 liver cirrhosis patients with BEV were selected as the observation group.60 liver cirrhosis patients with no BEV were selected as the control group. The two groups were observed of age and the degree of esophageal varices, portal vein diameter(PVD), splenic vein diameter(SVD),thickness of spleen(SPT), the maximum depth of ascites fluid dark area(ASmax) and other related ultrasound index. Laboratory indexes were including prothrombin time(PT), serum total bilirubin(TBIL),serum albumin(ALB). Results The average age of the observation group was(52.71±4.33) years old, which was higher than(46.83±5.19)years old of the control group(t= 4.08,P< 0.05).The liver function(Child-pugh) Grade A and grade C in the observation group patients were 78.33% and 0.00%, and compared with the control group,the difference was significant statistically(χ2= 4.97,P< 0.05). Esophageal varices with severe and mild of the observation group were 80.00% and 1.67%,and compared with the control group,the difference was statistically significant(χ2= 4.08,5.48,P< 0.05).RC of the observation group was 78.33%,which was higher than 30.43% of the control group(χ2= 5.11,P< 0.05).PVD,SVD,SPT and ASmax of the observation group were(16.05±3.14)mm,(11.24±3.21)mm,(46.90±6.26)mm and(57.91±6.11)mm,respectively,and compared with the control group,the differences were significant statistically(t= 4.37,6.12,5.18,7.22,all P<0.05).PT of the observation group was(17.66±2.08)s,which was higher than(13.93±1.67)s of the control group(t= 4.75,P<0.05).TBIL of the observation group was(172.63±16.50)μmol/L,which was higher than(138.44±12.71)μmol/L of the control group(t= 5.44,P< 0.05).ALB of the observation group patients was(27.36±3.44)g/L,which was lower than(30.85±2.75)g/L of the control group(t= 7.09,P< 0.05). Conclusion Age, liver function, PT and RC,PT, ASmax, PVD were related risk factors of patients with BEV. Key words: Esophageal and Gastric Varices; Hemorrhage; Liver Cirrhosis; Risk Factors