Analysis of the dynamic behavior of neuron populations in the turtle cerebellum. II. Lumped circuit model.

Abstract

A lumped circuit model was constructed which consisted of two input channels, climbing fiber and mossy fiber afferents, which described the magnitudes of synaptic transmission and which accounted for synaptic and transmission delays. The parameters and coefficients of the transfer function were chosen such that they corresponded to physiological observable quantities. The corresponding time function approximated the data points. The results indicated that the dynamic behavior of the cerebellar circuit was satisfactorily accounted for by a parallel excitatory and inhibitory system with a combined climbing fiber and mossy-parallel fiber input exciting the Purkinje cells. The initial negative was predominantly a climbing fiber response of the Purkinje cell supporting the inference which was derived from purely electrophysiological data.