Analysis of serious adverse drug reactions in 2016 from Qingdao of Shandong province

Abstract

Objective To analyze characteristics of serious adverse drug reaction from Qingdao and provide reference for clinical applications. Methods 1 130 reports collected by Qingdao Center for ADR Monitoring in 2016 were analyzed using retrospective study method. Results The antibiotics, traditional Chinese medicine injection and antitumor drug caused the higher proportion of serious adverse drug reaction.Injection was the main way for administration, which induced 73.45% of serious adverse drug reaction.65.00% cases with allergic shock occurred within 10min.Levofloxacin lactate injection caused the highest proportion of serious adverse drug reaction, Danhong injection caused the highest proportion of allergic shock reaction, Reduning injection caused the highest proportion of serious adverse drug reaction in children. Conclusion Safety monitoring for antibiotics, traditional Chinese medicine injection and antitumor drug should be further strengthened, including children adverse reactions. Key words: Adverse drug reaction reporting systems; Shock; Analysis