Analysis of risk factors for intracranial hemorrhage after cranioplasty

Abstract

Objective To analyze the risk factors of intracranial hemorrhage after cranioplasty. Methods A total of 278 patients with skull defect undergoing cranioplasty admitted to Department of Neurosurgery, Third Medical Center of PLA Gerneral Hospital from November 2010 to November 2018 were analyzed retrospectively. Patients were divided into 2 groups according to whether there was intracranial hemorrhage or not. Univariate analysis and multivariate Logistic regression analysis were used to identify the independent risk factor of epilepsy after cranioplasty. Results Of the 278 patients, 12 experienced intracranial hemorrhage after cranioplasty with an incidence of 4.3%. Univariate analysis showed that the area of defect and the time of skull defect were related to the occurrence of intracranial hemorrhage, the difference was statistically significant (P<0.05). multivariate Logistic regression analysis showed that the area of intracranial defect (≥100 cm2) was an independent risk factor of intracranial hemorrhage after cranioplasty (P<0.05). Conclusion The area of skull defect is the clinical risk factor of intracranial hemorrhage after cranioplasty. It is of important clinical significance for intracranial hemorrhage after cranioplasty to focus on the above indexe assessment. Key words: Cranioplasty; Intracranial hemorrhage; Skull defect area