Analysis of phonocardiogram signals through proactive denoising using novel self-discriminant learner.

Abstract

Phonocardiogram (PCG) records heart sound and murmurs, which contains significant information of cardiac health. Analysis of PCG signal has the potential to detect abnormal cardiac condition. However, the presence of noise and motion artifacts in PCG hinders the accuracy of clinical event detection. Thus, noise detection and elimination are crucial to ensure accurate clinical analysis. In this paper, we present a robust denoising technique, Proclean that precisely detects the noisy PCG signal through pattern recognition, and statistical learning. We propose a novel self-discriminant learner that ensures to obtain distinct feature set to distinguish clean and noisy PCG signals without human-in-loop. We demonstrate that our proposed denoising leads to higher accuracy in subsequent clinical analytics for medical investigation. Our extensive experimentations with publicly available MIT-Physionet datasets show that we achieve more than 85% accuracy for noisy PCG signal detection. Further, we establish that physiological abnormality detection improves by more than 20%, when our proposed denoising mechanism is applied.