Abstract

A method using a microfluidic chip coupled with contactless conductivity detection (C(4)D) is demonstrated for the determination of ofloxacin in Ofloxacin Ear Drops. Settings, optimizing procedures, electrophoresis conditions, regression equations, and the average recovery rate are discussed. Under optimum conditions, the determination of ofloxacin in standard solution is achieved within 1 min, which allows detection of ofloxacin in Ofloxacin Ear Drops. The demonstrated method is rapid, high efficient, sensitive, and economical.

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