Abstract

A selective and sensitive method was developed for the determination of heterocyclic amines (HCAs) by gas chromatography (GC). HCAs were converted into their N-dimethylaminomethylene derivatives and measured by GC with nitrogen-phosphorus selective detection using two connected fused-silica capillary columns containing DB-1 and DB-17ht. The derivatives of the 10 HCAs were sufficiently volatile and stable to give single symmetrical peaks. The calibration curves for HCAs in the range 0.5–10 ng were linear with correlation coefficients being above 0.998. The detection limits at a signal-to-noise ratio of 3 were ca. 2–15 pg per injection.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.