Abstract
The potential of using the information of uterine contractions (UCs) derived from electrohysterogram (EHG) has been recognized in early detection of preterm delivery. A better understanding of the conduction property of EHG is clinically useful for developing advanced methods to achieve a reliable prediction of preterm delivery. In this paper, a method to analyze the destination of EHG propagation has been proposed via the estimation of directed information (DI) between each pair of neighboring channels with a novel propagation terminal zone (PTZ) identification algorithm. The proposed method was applied to experimental data from the Icelandic 16-electrode EHG database. The results demonstrated that for more than 81.8% participants, the PTZ was identified along the medial axis of uterus, among which more than half have their PTZ determined in the center between the uterine fundus and public symphysis, which indicated a great probability of propagation of EHG signals towards the center of uterus plane.Clinical relevance- This study makes a fundamental contribution for predicting preterm delivery, which can provide improvement in obstetric care towards pregnancy monitoring.
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