Analysis of D1S80 VNTR Allele Polymorphism and Association with a Nearby Flanking Sequence Polymorphism in Two Spanish Populations

C Albarrán,M Sancho,P Martín,D N Stivers,O García,R Deka,R Chakraborty,A Alonso

doi:10.1007/978-3-642-80029-0_39

Analysis of D1S80 VNTR Allele Polymorphism and Association with a Nearby Flanking Sequence Polymorphism in Two Spanish Populations

C Albarrán, M Sancho + Show 6 more

https://doi.org/10.1007/978-3-642-80029-0_39

Copy DOI

Publication Date: Jan 1, 1996

Citations: 2

Affiliation: Instituto Nacional de Toxicología y Ciencias Forenses, Gobierno de Canarias, Basque Government, University of Pittsburgh, The University of Texas Health Science Center at Houston

#Variable Number Of Tandem Repeats #Number Of Repeats + Show 8 more

Abstract
Full-Text PDF
Similar Papers

Abstract

Variable number of tandem repeats (VNTR) loci are highly informative markers for linkage analysis and identity testing. In addition to the variation in the number of repeats, some VNTR loci display variabilty of the repeat sequence so that an additional polymorphism level can be observed analyzing the interspersion pattern of variant repeats along the tandem repeat array (Jeffreys et al. 1991; Neil and Jeffreys 1993). For the majority of VNTR loci, however, the extent of polymorphism of the flanking sequences is not known, despite some early studies showing linkage between VNTR specific-alleles and nearby RFLPs (Higgs et al. 1986; Cox et al. 1988; Renges et al. 1992; Martinson et al. 1994).

Full Text