Analysis of curative effect of low temperature plasma combined with collagenase guided by computer tomography on lumbar intervertebral disc herniation

Abstract

Objective To investigate the efficacy of CT-guided low-temperature plasma-mediated radiofrequency ablation combined with collagenase in the treatment of prolapse of lumbar intervertebral disc. Methods A total of fifty-eight patients with prolapse of lumbar intervertebral disc received low-temperature plasma-mediated radiofrequency ablation combined with collagenase were retrospectively analyzed. Changes in the degree of pain before and after operation were evaluated by VAS. The duration of postoperative recovery and pain relief were recorded. Risk factors for postoperative pain relief were analyzed. Results All patients underwent successful puncture, and no neurological injury, intervertebral disc infection, and no complications such as spinal cord and vascular organ injury. Postoperative follow-up for 6 months, the mean VAS was 3 points after 2 weeks. The mean VAS was 2.6 points at 1 month postoperatively, which was statistically different from the 2 weeks postoperatively (P 0.05). MacNab evaluation was excellent. A total of 30 patients (51.7%) had a good evaluation of 15 patients (25.8%), and 8 patients (15.5%) had a good evaluation. The patients with poor results were 5 patients (7%). The excellent rate reached 89.7%. Conclusions Low-temperature plasma-mediated radiofrequency ablation combined with collagenase can effectively treat prolapse of lumbar intervertebral disc. These two techniques are both characterized by safety and minimal trauma. Thus, this method is recommended for combined minimally invasive interventional therapy in addition to conservative therapy and open surgery. Key words: Low-temperature plasma-mediated radiofrequency ablation; Collagenase; Prolapse of lumbar intervertebral disc; Computer tomography