Analysis of correlation between hyperuricemia and blood lipids of the elderly in Hebei Renqiu

Abstract

Objective To investigate the hyperuricemia(HUA)and the correlation of blood lipids of the 60-70years peple in Renqiu area, and to provide the basis for guiding prevention and treatment of the elderly disease the region. Methods According to the cluster random sampling method, Renqiu permanent residents with the age of 60 to 70 years were selected as a screening object. In the total 5 010 cases screened object, 2 163 were male(43.2%),2 847 were female(56.8%), with an average age of(64.29±3.05)years. The data of blood uric acid and total cholesterol(TC), triglyceride(TG), high-density lipoprotein(HDL-C), low-density lipoprotein(LDL-C)were collected. The rela-tionship between blood uric acid and blood lipids were analyzed. Logistic regression method was used to analysis the relationship between the hyperuricemia and lipids components. Results The overall prevalence of hyperuricemia in Renqiu was 6.1%(9.8% in male,3.2% in female). In men HUA group, the levels of blood uric acid, TG and LDL -L were 464.10(438.00-508.65)μmol／L,1.54(1.00-2.19)mmol／Land 2.66(2.25-3.22)mmol／L, which were higher than those of normal uric acid group of 294.00(249.90-338.08)μmol／L,1.13(0.84-1.65)mmol／L and 2.57(2.12-3.01)mmol／L(P＜0.05). In women HUA group, the levels of blood uric acid, TG and LDL-L were 454.15(434.15-480.78)μmol／L,2.14(1.47-3.18)mmol／L and 2.96(2.52-3.76)mmol／L, which were higher than those of normal uric acid group of 250.80(209.00-299.80)μmol／L,1.53(1.10-2.20)mmol／L and 2.87(2.40-3.33)mmol／L(P＜0.05). Logistic multi-factor regression analysis showed that TG was an independ-ent risk factor for hyperuricemia, and that HDL-L and gender were protective factors. Conclusion Hyperuricemia is closely associated with blood lipid, especially with TG and HDL-L, so we could screening HUA by blood lipid, which can reduce the occurrence of cardiovascular disease effectively. Key words: Uric acid; Hyperuricemia; Blood lipid