Abstract
Analysis of Content and In-Vitro Effect of Sodium Bicarbonate in Gripe Water Administered to Infants
Highlights
Gripe water was initially formulated as a mixture of dill seed oil, sodium bicarbonate, and alcohol along with other ingredients to soothe colic in babies
Consumption of sodium bicarbonate need not always be safe since it can cause a condition called milk-alkali syndrome. In this condition the amount of calcium in the blood increases due to a high intake of milk calcium and sodium bicarbonate which is alkaline
The solution was stirred on magnetic stirrer, and 0.1N HCl solution was added in 1 mL aliquots and pH change was measured
Summary
Gripe water was initially formulated as a mixture of dill seed oil, sodium bicarbonate, and alcohol along with other ingredients to soothe colic in babies. Sodium bicarbonate is still an important constituent in gripe water. Consumption of sodium bicarbonate need not always be safe since it can cause a condition called milk-alkali syndrome. In this condition the amount of calcium in the blood increases due to a high intake of milk calcium and sodium bicarbonate which is alkaline. Babies younger than six months which consume only breast milk, are at a greater risk of encounter this syndrome, if constantly given gripe water. Premature babies and babies born with kidney problems are advised not to be given sodium bicarbonate
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