Abstract
BackgroundRecurrent spontaneous abortion has been reported tooccur in 15-20% of all clinically recognizable pregnancies.Numerous studies have reported a clear relationshipbetween the chromosomal abnormalities in parents andrecurrent miscarriages and infertility [1-3], however lim-ited data is available from Arabian Peninsula. The maingoal of this study was to determine the prevalence ofchromosomal abnormalities and correlate them with clini-cal characteristics of couples with recurrent spontaneousabortions (RSA) in Saudi Arabia.Materials and methodsCytogenetic analysis of 171 consent patients with sponta-neous recurrent abortions was performed by the standardmethod of 72-hour lymphocyte culture and GTG banding.
Highlights
Recurrent spontaneous abortion has been reported to occur in 15-20% of all clinically recognizable pregnancies
Materials and methods Cytogenetic analysis of 171 consent patients with spontaneous recurrent abortions was performed by the standard method of 72-hour lymphocyte culture and GTG banding
Our results showed that 6.43% of patients are carrier of a chromosomal abnormality
Summary
Recurrent spontaneous abortion has been reported to occur in 15-20% of all clinically recognizable pregnancies. Numerous studies have reported a clear relationship between the chromosomal abnormalities in parents and recurrent miscarriages and infertility [1,2,3], limited data is available from Arabian Peninsula. The main goal of this study was to determine the prevalence of chromosomal abnormalities and correlate them with clinical characteristics of couples with recurrent spontaneous abortions (RSA) in Saudi Arabia
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