Analysis of Birth Defect Monitoring Data and Comparison of Prediction Models in Lanzhou, China

Guangzhuang Jing,Jun Zhang,Zhilan Li,Yanjun Yang,Qingli Bai,Li Pan,Li’Ao Xie

doi:10.33582/2639-4391/1018

Abstract

Analysis of Birth Defect Monitoring Data and Comparison of Prediction Models in Lanzhou, China

Highlights

Birth Defects (BDs) consist of a group of conditions, including physical or biochemical abnormalities, present at birth, which may involve malformations, disruptions, deformations [1,2]
The average prevalence rate of total perinatal infants’ birth defects was 104.13 per 10000 perinatal infants in the past 7 years in Lanzhou, with an upward trend increasing by 7.74% on average each year
Congenital heart disease and Polydactylism are the main types of birth defects, which should be strengthened in the future

Summary

Introduction

Birth Defects (BDs) consist of a group of conditions, including physical or biochemical abnormalities, present at birth, which may involve malformations, disruptions, deformations [1,2]. The World Health Organization (WHO) estimates that approximately 260,000 deaths (7% of all neonatal deaths) globally were caused by BDs in 2004. The prevalence rates of BDs is estimated reach to 4.7% in the developed countries, 5.6% in the middle-income countries, and 6.4% in the low-income countries [6,7]. As far as we know, China is the most populated developing country in the world, and the prevalence of BDs varies across different socioeconomic groups and areas [8]. China is a middle-income country with the largest population in the world, which has 16 million births annually and is expected to have 0.9 million BDs each year [9]. To analyze the distribution of birth defects in Lanzhou, China from 2012 to 2018, to forecast the prevalence in the future, and to provide evidence for prevention of birth defects

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Methods

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Conclusion