Analysis of 25 (OH) D levels in children aged 0-12 years in Quanzhou area

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Objective To study the serum level of 25(OH)D in children aged 0-12 years in Quanzhou, Fujian Province. Methods The clinical data at serum levels of 25(OH)D in children aged 0-12 years old in Quanzhou Women and Children′s Hospital were analyzed retrospectively from January 1, 2016 to May 31, 2017.The nutritional status of vitamin D in children at different genders, age and seasons were analyzed.All the subjects were divided into 3-6 years old group, and >6 years old group. Results A total of 5 830 children aged 0-12 years were included in this study.The serum 25(OH)D level was (68.85±22.53) nmol/L, and among them there were 4 682 cases (80.31%) of vitamin D abundant, 723 cases (12.40%) of vitamin D insufficient, 425 cases (7.29%) of vitamin D deficiency, and 0 case of both vitamin D overdose and poisoning.The levels of vitamin D in children in different seasons were different, and the levels of serum 25(OH)D in summer[(76.20±22.25) nmol/L] were significantly higher than those in other 3 seasons [vitamin D in spring, autumn and winter was (68.35±22.08) nmol/L, (62.35±21.88) nmol/L, (66.13±21.78) nmol/L, respectively], and the differences were all statistically significant (all P 0.05), while the levels of which were higher in boys in both >3-6 years old group and >6 years old group than those in girls [(64.63±19.53) nmol/L vs.(59.78±17.88) nmol/L, (57.63±16.65) nmol/L vs.(51.00±15.58) nmol/L], and the differences were all statistically significant (all P 3-6 years old group, >6-years old group were (84.08±26.93) nmol/L, (78.43±22.50) nmol/L, (64.43±19.55) nmol/L, (59.20±19.00) nmol/L], and the differences were all statistically significant (all P<0.01). Conclusions The serum levels of 25(OH)D in children aged 0-12 years in Quanzhou area are comparatively fine.Vitamin D supplementation in children over 3 years old should not be ignored. Key words: Child; 25(OH)D; Vitamin D