Abstract
A special purpose analog computer is designed to study the normal human ventilatory response to increasing concentrations of carbon dioxide. An infrared analyzer and a pneumotachograph and strain gauge are the transducers. Standard chopper-stabilized operational amplifiers and one nonlinear (divider) element are used. A relay system synchronizes the timing and readout of the signals to produce an x-y plot of alveolar ventilation and alveolar carbon dioxide tension. This relation is used as a measure of the sensitivity of the respiratory center and of its depression by narcotic drugs.
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