Abstract

Tuberculosis (TB) is a direct infectious disease caused by Mycobacterium tuberculosis. Anti-tuberculosis drugs have a hepatotoxic effect that causes extensive liver injury and harvesters. The parameter to determine the presence or absence of liver damage is to look at SGPT and SGOT levels. The purpose of this study was to determine the effect of drugs on SGPT and SGOT values based on age and sex classification. The method is carried out with a retrospective approach. The results showed that the effect of drugs on the value of SGPT with a high value of> 35 as much as 6.25%, on the value of SGOT with a high value> 35 as much as 12.5%. Whereas at the age of 56-65 years the SGPT value was 2.5% and SGOT was 3.75%, at the age of 17-25 years the SGOT value was 3.75%. sex with a high SGPT score of 5%. While the SGOT value is equal to 6.25%. Then it can be concluded that the administration of anti-tuberculosis drugs to the value of SGPT and SGOT has an effect on the value of SGPT and SGOT based on age is productive age which is 15-49 years whereas based on gender is men.

Highlights

  • The results showed that the influence of the highest Obat Anti tuberkulosis (OAT) on Serum Glutamic Pyruvic Transaminase (SGPT) values was at the age of 56 -65 years by 2.5%, while the highest OAT effect on the value of Serum Glutamic Oxaloacetic Transaminase (SGOT) at ages 17-25 and 56-65 years was 3.75%

  • Gambaran nilai Serum Glutamic Oxaloacetic Transaminase (SGOT) dan Serum Glutamic Pyruvic Transaminase (SGPT) pasien tuberkulosis paru yang dirawat inap di RSUD Arifin Achmad Provinsi Riau tahun 2013

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Summary

Article Info

Tuberkulosis (TB) adalah penyakit infeksi yang disebabkan oleh bakteri Mycobacterium tuberculosis. Parameter untuk menentukan ada atau tidaknya kerusakan hati adalah dengan melihat kadar SGPT dan SGOT. Tujuan penelitian ini adalah mengetahui pengaruh OAT terhadap nilai SGPT dan SGOT berdasarkan klasifikasi usia dan jenis kelamin terhadap pasien tuberkulosis paru yang dirawat inap di RS Sari Asih Ciputat periode Januari sampai Juni 2018. Hasil penelitian menunjukan bahwa pengaruh OAT tertinggi pada nilai SGPT adalah pada usia 56 -65 tahun sebanyak 2,5%, sedangkan pada pengaruh OAT tertinggi pada nilai SGOT pada usia 17-25 dan 56-65 tahun sebanyak 3,75%. Selanjutnya, pengaruh OAT tertinggi terhadap nilai SGPT adalah jenis kelamin perempuan sebanyak 5%, sedangkan nilai SGOT antara perempuan dan laki-laki adalah sama, yaitu sebanyak 6,25%. Kesimpulan dari penelitian ini adalah pemberian OAT terhadap nilai SGPT dan SGOT berpengaruh pada usia dan jenis kelamin

Berdasarkan data dari World Health
Nasional oleh Kementrian Kesehatan
WHO telah merekomendasikan strategi
KDT Kombipak
Tidak sesuai
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