Abstract

Anti-N-methyl-D-aspartate (NMDA) receptor (NMDA-R) encephalitis is a recently described neurological disorder, an immune-mediated encephalitis caused by production of antibodies to the NMDA-R, now a recognised cause of psychosis, movement disorders and autonomic dysfunction.[1,2] Though it is the second most frequent cause of immune-mediated encephalitis, it is usually under-diagnosed. Many anaesthetic medications interact with NMDA-Rs with risks during induction and maintenance of anaesthesia.[3] We report a patient with documented anti-NMDA-R encephalitis who was scheduled for surgery for right salpingo-oophorectomy under general anaesthesia.

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