Abstract

ABSTRACT Mucinous colorectal adenocarcinoma represents a distinctive variant of colorectal carcinoma (CRC), which is typified by copious amounts of extracellular mucin. This subtype of CRC is distinguished by the presence of mucin, which constitutes at least 50% of the tumor volume, thus serving as a defining histologic feature of this malignancy. Colorectal carcinoma patients may develop lymphocytic and hematogenous metastases. While surgery is the only curative treatment option available, the use of chemotherapy, radiation therapy, or a combination of both can help improve the prognosis. However, the risk of recurrence remains substantial, in terms of both locoregional and distant spread. This article reports a gingival metastatic carcinoma of colorectal mucinous adenocarcinoma in a 24-year-old woman. Microscopically, architectural and cellular features resulted in ruling out differentials. Oral metastases are an infrequent phenomenon that can arise within either the soft tissues or the osseous structures of the oral cavity. This metastasis can exhibit clinical and radiographic features that are reminiscent of clear cell lesions localized in the head and neck region.

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