An Unusual Presentation of Glucose Six Phosphate Dehydrogenase Deficiency in a Toddler: A Case Report

Abstract

ABSTRACT Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common worldwide inherited red cell enzymopathy which may have a varied presentation. It usually comes to attention when exposed to oxidative agents leads to an acute hemolytic crisis with a sudden dip in hemoglobin levels. G6PD deficiency may also present as neonatal jaundice. Respiratory distress is an unusual presentation of G6PD deficiency especially when a respiratory infection is ruled out. We hereby present a case of G6PD deficiency in an 18-month-old toddler who presented with an acute hemolytic crisis with respiratory distress. The myriad of symptoms of G6PD deficiency must be kept in mind, and it is important that caution be exercised while prescribing oxidative drugs to patients with G6PD deficiency.