Abstract
Focal oral mucinosis (OFM) is a rare lesion of unknown etiology that exhibits tumor growth. OFM has a predilection for keratinized tissues, such as the gingiva or hard palate. The occurrence of OFM in nonadherent oral mucosa is rare. Here we present the case of a 47-year-old woman, nonsmoker, nonalcoholic, with no history of facial trauma. On extrabuccal examination, no changes were observed. On intraoral examination, a 10 × 10 mm yellow submucosal rounded nodule was observed in the lower midline fornix region, fibrous on palpation, covered by thin and normal mucosa. On occlusal radiography, no bone destruction was observed. Excisional biopsy was performed. Histomorphologic analysis showed myxoid connective tissue with abundant mucinous material with delicate collagen fibrils. The diagnosis of OFM was established by staining with Alcian blue, period acid-Schiff stain, and immunohistochemistry for protein S-100. In 1 year of follow-up, there was no recurrence.
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