An unusual case of enterococcal tricuspid valve endocarditis

Abstract

A 52-year-old male smoker presented with a 10-week history of weight loss and malaise, together with a 1-week history of left-sided pleuritic chest pain, haemoptysis and mild dyspnoea. He had used intravenous drugs for a short time 30 years previously although he denied any intravenous drug use since. There was no other past medical history of note. On examination, he was thin and appeared chronically unwell. He was apyrexial. There was a left pleural rub. There were no murmurs or stigmata of endocarditis. There were no other findings of note. Full blood screen was normal apart from a white cell count of 11.2x109/litre (normal range 4.0–11.0x109/litre). Erythrocyte sedimentation rate was 52 mm/hr and C-reactive protein was 16 mg/litre (normal range <7.0 mg/litre). Urinalysis and urine culture were normal. The chest X-ray showed a circumscribed left lower zone lesion (Figure 1). Figure 2 shows the computed tomography appearance of the lesion. At this stage, pulmonary malignancy was suspected (either a primary or secondary). The following day, two sets of blood cultures were taken in view of a low grade pyrexia. Enterococcus faecalis grew from all four bottles and the patient was started on intravenous amoxycillin. Five days after admission a new soft pansystolic murmur at the left sternal edge was noted. Intravenous gentamicin was added. Transthoracic echocardiogram was normal but was repeated after an interval of 10 days in view of continuing low grade pyrexia and at this stage showed a vegetation adherent to the tricuspid valve (Figure 3). The patient was treated with intravenous amoxycillin and gentamicin for a total of 6 weeks. He did not develop any further complications and has remained well at follow up.