Abstract
Treatment of 23E-benzylidenespirostanes with BF3·Et2O in 2/1 acetic acid/CH2Cl2 led to novel steroids bearing a spiro[furan-indene] moiety in the side chain. When steroid sapogenins were treated with benzaldehyde and BF3·Et2O in the same mixture of solvents, similar compounds were obtained. The structures of the novel spirocyclic steroids were confirmed by NMR and X-ray diffraction.
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