Abstract
Ectomesenchymal chondromyxoid tumor (ECT) is a rare benign tumor that occurs mainly in the tongue. ECTs on the hard palate are exceedingly rare. We report the clinicopathologic and immunohistochemical features of a rare case of ECT in a 22-year-old male patient positive for human immunodeficiency virus who presented a painless multilobulated swelling measuring 2.0 cm in diameter on the hard palate. Panoramic radiograph revealed no bone changes. An incisional biopsy was performed. Microscopically, the tumor was well-circumscribed and composed of spindle and ovoid cells organized in a lobular arrangement in a chondromyxoid stroma. Immunohistochemistry showed positivity for protein S-100, GFAP, and D2-40. Pan-cytokeratin AE1/AE3, CD34, CD31, and HHV8 were negative. The diagnosis was ECT. The treatment was conservative surgical removal. At 6-month follow-up, no evidence of recurrence was observed. Clinicians and pathologists should consider ECT in the differential diagnosis of oral soft tissue lesions to provide adequate management through conservative surgical removal.
Published Version
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