Abstract
The sea nettle ( Chrysaora quinquecirrha) and Portugese man-o'war ( Physalia physalis) venoms induced changes on cultured Chinese hamster ovary K-1 cells consisting of nuclear alterations (multi-nucleated cells, multiple nucleoli in the nucleus and a loss of peripheral chromatin) and dissolution of intercellular collagen. It is hypothesized that these changes are a result of the collagenase, protease and lectin-like activities of the venoms.
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