Abstract
Cancer Chemotherapy In article number 2200765 by Jeewon Lee and co-workers, optimized structures to enable cancer cell-specific activation of chemotherapeutic drugs are constructed through integrating core peptide units into highly-ordered, stable, and guest-adaptable structures of human heavy chain ferritin (huHF) scaffolds. After endocytosis to cancer and normal cells, the drugs are released from huHF-drug conjugates in cancer cells, whereas in normal cells, the huHF-drug conjugates remain inactive without drug release.
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