Abstract
Abstract This paper describes a hybrid computing system for on-line human respiratory studies. A digital computer dictates the subject's inspired CO2 concentration through a servocontrolled breathing chamber. The inspired CO2 is varied so that the alveolar CO2 concentration has a useful dynamic perturbation. A special purpose analog computer system measures and displays respiratory response data in real time and an on-line digital system accumulates these data on a breath-to-breath basis. A digitally controlled breath sound simulator is used to study the subject's voluntary interaction with his involuntary CO2 response. Examples of experimental data are presented. The system is presently in use in ongoing studies of the normal and drug-altered respiratory control system.
Published Version
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