An investigation on the replacement of antibiotics by medicinal plants to control the infection of Escherichia Coli (E. coli) in broiler chickens

Abstract

This study was done to determine the effects of garlic, mint and onion in feeding of the broiler chickens as a growth natural factor (GNF) instead of antibiotics. First, the antibacterial effects and minimum inhibitory concentration (MIC) of 0.5, 1, 2.5, 5, 10 and 20% concentrations of aqueous extracts of garlic (Allium sativum), mint (Mentha spp.) and onion (Allium cepa) on E. coli were determined in in vitro conditions. Results show that the minimum inhibitory concentration (MIC) of garlic extract was 0.5%. Distilled water, phenol phenicol and Floxacin were used as solvent and control. In the next step, the effects of adding garlic to the diet of broiler chickens were analyzed at farm. 300 day-old broilers (Arbor Acres Plus) were divided into groups of 60 birds each and randomly assigned to the five treatment diets. Each treatment has three replicates. These chickens were kept up to the age of 56 days (8 weeks), all under study and fed with the standard ration. According to the corrections, adding 8% garlic to the diet was equal to the minimum inhibitory concentration (MIC) in the lab. As a result, we used garlic itself instead of its aqueous extract in the diet. The different experimental groups did not receive any antibiotic and growth additives. The different experimental groups were as follows. The 1 st group which