Abstract
An in vitro study on the effect of synthesized tin(IV) complexes on glioblastoma, colorectal, and skin cancer cell lines
Highlights
From the late 1960s until the present, there have been significant advances in both the early detection and the treatments of cancer
We evaluated the effect of compounds 1-3 on the cancer cell lines (colorectal (HT-29, HCT-116) and skin (A431)) and a normal skin cell line (HFF)
The anti-cancer properties of compounds 1-3 were evaluated in two colon cancer cell lines, HT-29 and HTC-116
Summary
From the late 1960s until the present, there have been significant advances in both the early detection and the treatments of cancer. Despite these advances overall incidences of cancer and deaths from cancer have increased during the same period [1]. These counterintuitive increases have been the impetus for development of new drugs for cancer treatment. In this context the organometallic compounds have been widely investigated as potential anti-tumour agents. Ferricenium salts, organotin, and bismuth complexes have emerged as examples of organometallic compounds that have been found to exhibit interesting anti-tumour activity [5]
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