Abstract
Being the most common glial cell tumor of the adult brain, primary glioblastoma multiforme is an extremely rare but excessively devastating condition of the spinal cord. It presents with indistinctive magnetic resonance imaging findings, so the diagnosis is very complicated to make. A low-grade glioma may undergo a malignant transformation into glioblastoma multiforme in a very short period, critically impairing treatment possibilities and prognosis, so a correct and timely diagnosis is crucial. We report a case of intramedullary glioblastoma multiforme in a young man and describe the diagnostic difficulties and devastating progression of the entity.
Highlights
Glioblastoma multiforme (GBM) of the spinal cord is an exceptionally rare but remarkably aggressive tumor of the spinal cord, comprising only about 2%–4% of all glial tumors of the central nervous system (CNS) [1]
The diagnosis is very complicated to make because intramedullary GBM, being extremely rare, presents with unspecific magnetic resonance imaging (MRI) findings
No pathological changes were found during spinal angiography, computed tomography (CT) of the abdomen and the pelvis, chest x-ray examinations, as well as MRI examination of the head
Summary
Being the most common glial cell tumor of the adult brain, primary glioblastoma multiforme is an extremely rare but excessively devastating condition of the spinal cord. It presents with indistinctive magnetic resonance imaging findings, so the diagnosis is very complicated to make. A low-grade glioma may undergo a malignant transformation into glioblastoma multiforme in a very short period, critically impairing treatment possibilities and prognosis, so a correct and timely diagnosis is crucial. We report a case of intramedullary glioblastoma multiforme in a young man and describe the diagnostic difficulties and devastating progression of the entity
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