Abstract

We herein report glutathione (GSH) detection in water using an organic field-effect transistor (OFET) with a solution-processable small molecule semiconductor. The fabricated OFET operated reproducibly at below ∣3∣ V. The sensing portion for GSH in the OFET is an extended-gate electrode made of gold (Au). Owing to the strong binding of GSH with Au through chemisorption, we have successfully observed a shift of threshold voltage of the OFET upon addition of GSH in an aqueous solution. Because GSH is important for our body, the device would be applied to various research fields including molecular biology, analytical chemistry, and medical diagnostics.

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