Abstract
This review aimed to provide a comprehensive overview of ethnobotanical uses, chemical constituents, posology, and toxicology of Hyptis suaveolens, and to address the significant medicinal benefits in order to promote its application. An extensive and systematic review of the literature was undertaken and all relevant abstracts and full-text articles analyzed and included in the review. A wide range of traditional uses are cited in the literature, ranging from uses for malaria, constipation, stomach problems, renal inflammation to external uses in repelling insects and treating injuries such as lacerations and burnrelated damage to skin and tissues. To date, pharmacological studies have demonstrated the significant activities of this plant that support uses such as antimicrobial, antidiabetic, antiulcer, and antiinflammatory. Numerous important phytochemicals, including 6 triterpenes, 8 diterpenes and 1 flavonoid have been isolated, identified and reported. The extracts and phytochemicals isolated from the plants show considerable potential for medicinal exploitation and utilization, including antimitotic, antiproliferative, cytotoxic, antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, anti-secretory, hepatoprotective, insecticidal, and acaricidal activities. As a medicinal plant, H. suaveolens is endowed with immense exploitation and utilization value and is widely used worldwide Therefore, further studies to fully elucidate its medicinal potential are warranted.
 Keywords: Hyptis suaveolens (L.) Poit, Ulcer Antimicrobial Inflammation, Diterpenes, Traditional medicine, Ethnopharmacology, Lamiaceae
Highlights
Species of the family Lamiaceae, which are largely herbaceous and of economic importance, are found mostly in tropical, subtropical, and temperate parts of the world
Hyptis suaveolens (L.) Poit is belonging to the genus Hyptis and family Lamiaceae that includes 775 species worldwide, which are primarily found in South America
H. suaveolens (Fig. 1) is a fast-growing perennial and aromatic herb that is 0.4–2 m high with a include its characteristics, uses, chemical constituents, posology, phytochemistry and toxicology to facilitate the development and utilization of H. suaveolens
Summary
Species of the family Lamiaceae, which are largely herbaceous and of economic importance, are found mostly in tropical, subtropical, and temperate parts of the world. Hyptis suaveolens (L.) Poit is belonging to the genus Hyptis and family Lamiaceae that includes 775 species worldwide, which are primarily found in South America. Plants of the Hyptis genus have been highlighted for numerous medicinal properties such as tumorigenic, antifertility, antimicrobial, mycotoxic, and phytotoxic activities [1]. Among these plants, Hyptis suaveolens (L.) Poit is an important traditional medicinal plant that was originally native to tropical America and is currently considered as a weed worldwide. The plant is characterized by a strong minty smell when crushed Most parts of this plant are used in medicine formulations for treating numerous ailments such as respiratory and gastrointestinal infections, indigestion, colic, stomachache, colds, fever, burns, wounds, cramps and various skin complaints and it is used as an antirheumatic and antisuporific bath [4-6]
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